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Vitamin E isn’t a single nutrient. It’s a term used to describe a group of compounds with similar properties. Vitamin E compounds are broken down into tocopherols and tocotrienols. Maybe you’ve head of alpha-tocopherol. It’s one form of vitamin E. But there are 7 more found in nature that our bodies benefit from. These are beta, gamma, and delta tocopherol as well as alpha, beta, gamma, and delta tocotrienols. For simplicity’s sake, we will refer to this family of compounds as vitamin E.

Vitamin E is made by plants and are often (but not always) found in fatty foods. This is helpful to humans because vitamin E is a fat-soluble nutrient. This means vitamin E must be eaten with fat in order for it to be absorbed. It also means that vitamin E can be stored in your fat tissue for use when needed.


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*These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Osborne is not a medical doctor. He does not treat or diagnose disease. He offers nutritional support to people seeking an alternative from traditional medicine. Dr. Osborne is licensed with the Pastoral Medical Association.

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Here are the links to the research papers referenced in the video:
https://www.cochranelibrary.co....m/cdsr/doi/10.1002/1
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC17908
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC41690

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Make sure you’re getting the best type of vitamin E. Check this out. 

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DATA:
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC49846

Timestamps:
0:00 Vitamin E 
0:16 The vitamin E complex 
0:38 What type of vitamin E do people need more of? 
0:56 What are tocotrienols?
2:43 Vitamin E benefits
3:09 Sources of tocotrienols 
3:36 The best type of vitamin E 

Today we’re going to talk about the best type of vitamin E. In nature, vitamin E always comes in a complex. The vitamin E complex is composed of four tocopherols and four tocotrienols. When I mention four, I’m talking about the four different forms (alpha, beta, delta, gamma). 

The type of vitamin E that most people need more of is tocotrienols. You can very easily get tocopherols from the diet, so they usually aren’t needed in supplement form. Tocotrienols are more difficult to get from the diet. 

Tocotrienols are different from tocopherols in that they are 5000 times faster at handling free radicals. 

Vitamin E, in general, is a powerful lipid antioxidant, and one of the main functions is the protection of lipids. Lipids are in the cell membrane. Without vitamin E, all sorts of things can happen to the cell membranes. 

Tocotrienols are like little antioxidants that are spinning extremely fast to clean up and neutralize free radical damage. 

Potential benefits of vitamin E (especially tocotrienols):
• They may be anti-cancer. 
• They may be cardioprotective. 
• They may be liver-protective.
• They support the cell membranes of the skin, brain, nervous system, and the inside of the arteries.

Sources of tocotrienols:
• Rice (not keto-friendly) 
• Palm oil
• Annatto (might be one of the best sources) 

If you’re going to take vitamin E, it may be best to get the whole vitamin E complex, including both tocopherols and tocotrienols. Or you could try getting tocopherols from your diet, and get tocotrienols from a product made from annatto. 

Dr. Eric Berg DC Bio:
Dr. Berg, age 58, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg’s Nutritionals. He no longer practices, but focuses on health education through social media.

Follow us on FACEBOOK: fb.me/DrEricBerg



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Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

Make sure you’re getting the best type of vitamin E. Check this out.

Check out this video on what to do about dark circles under your eyes next! https://youtu.be/UzP3OJKfhhc?si=8xy4Ds3JM4C7nDOC

Is Vitamin C a regular part of your anti-aging skincare routine? Taking good care of your skin is vital to keeping your skin and overall appearance looking youthful, glowing, and healthy. A major part of that is to use the proper active ingredients that will help keep your skin looking great and functioning properly. Dr. Karam is a huge supporter of a consistent, high-quality skincare routine, and he always recommends using Vitamin C as a key part of your skincare regimen. Even though Vitamin C is such an important part of an effective skincare routine, there are a lot of myths and misunderstandings surrounding this incredible active ingredient! Today, Dr. Karam is breaking down the dos and don'ts of Vitamin C, so that you can rest assured that you are doing what is the absolute best for your skin!

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00:00 Vitamin C Dos and Don'ts
01:30 The Necessity of Vitamin C
03:30 Do 1: Use It!
03:58 Do 2: Use Consistently
05:38 Do 3: Use With Sunscreen
07:06 Do 4: Use With Retinol
09:20 Do 5: Have Patience
10:13 Do 6: Store Vitamin C Properly
10:47 Do 7: Use it on Neck & Eyes
12:19 Don't 1: Use Vitamin C & Retinol At Same Time
12:29 Don't 2: Use Vitamin C with AHAs
12:36 Don't 3: Use Too Much
13:28 Don't 4: Leave Lid Off Product
13:45 Don't 5: Quit!

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Liposomal Vitamin C vs Vitamin C: Benefits and Key Differences

Discover the differences between liposomal vitamin C and traditional vitamin C in this comprehensive breakdown. Learn how these two forms compare in terms of absorption, benefits, and ideal usage. Whether you’re looking for an immune boost, better skin health, or overall wellness, this guide will help you make the right choice for your needs. Explore the science behind liposomal technology and why it might be the future of vitamin C supplementation.

Read also: Liposomal vitamin C side effects: What You Need to Know: https://youtu.be/yfWjJX8-CvA
#2025 #liposomalvitaminc #vitaminc #healthtips #healthylifestyle

VITAMIN C & COVID? Real Doctor Explains Impressive Benefits of Vitamin C Supplements. Real doctor explains vitamin C benefits, vitamin C sources, vitamin C supplements, & why we need it. ER Doctor Dr. Jordan Wagner explains vitamin C foods, vitamin C tablets, vitamin C supplements, vitamin C benefits, vitamin C sources, and vitamin C dosage. Vitamins to prevent COVID? Vitamin C is one of the safest and most effective nutrients, experts say. Though it may not be the cure for the common cold, the benefits of vitamin C may include protection against immune system deficiencies, cardiovascular disease, prenatal health problems, eye disease, and even skin wrinkling. It helps form and maintain bones, skin, and blood vessels. It is also an antioxidant. You've probably also watched all of those DIY beauty and skincare routine videos on how to make vitamin C serum at home videos but does vitamin C help acne and give you energy? Or you've heard that vitamin c and result in glowing skin, open pores, and get rid of dark pigmentation or hyperpigmentation. Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement. If you have any medical questions, vitamin C questions, or even a funny COVID-19 quarantine vlog, send it my way! Thanks so much for watching. Stay healthy, my friends!

OTHER VIDEOS ABOUT VITAMIN C:

@Dr. Eric Berg DC - Vitamin C's Immune Benefits
https://www.youtube.com/watch?v=ivYMo59SRRI

@Dr. Sten Ekberg - CoronaVirus (COVID-19) Top 10 Vitamin C Foods You Must Eat https://www.youtube.com/watch?v=BzpaALfeR2g

@MedCram - Medical Lectures Explained CLEARLY - If You Get COVID 19: Optimize Immune System (Vitamin D, Monoclonal Antibodies, NAC, Quercetin etc.)
https://www.youtube.com/watch?v=vN30emwcNS4&feature=youtu.be

@Christy Risinger, MD - Vitamins to Prevent COVID???
https://www.youtube.com/watch?v=H2V4U218osU

@Doctor Mike Hansen - Doctor Vitamin C, Vitamin D and COVID - Prevention of COVID
https://www.youtube.com/watch?v=UAHhhweamIU

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LINKS & REFERENCES:

Coronavirus Disease 2019 (COVID-19) | CDC
https://www.cdc.gov/coronaviru....s/2019-ncov/index.ht

Coronavirus disease (COVID-19) | WHO
https://www.who.int/emergencie....s/diseases/novel-cor

Vitamin C Fact Sheet for Health Professionals | National Institutes of Health
https://ods.od.nih.gov/factshe....ets/VitaminC-HealthP

Vitamin C | MedlinePlus
https://medlineplus.gov/vitaminc.html

Vitamin C - Medical Encyclopedia | MedlinePlus
https://medlineplus.gov/ency/article/002404.htm

High-Dose Vitamin C (PDQ®)–Patient Version | National Cancer Institute
https://www.cancer.gov/about-c....ancer/treatment/cam/

The Effects of High Concentrations of Vitamin C on Cancer Cells | Nutrients
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC37989

High-Dose Intravenous Vitamin C Combined with Cytotoxic Chemotherapy in Patients with Advanced Cancer: A Phase I-II Clinical Trial | PLoS One
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC43886

Vitamins C and E Tied to Lower Risk for Parkinson’s Disease | The New York Times
https://www.nytimes.com/2021/0....1/13/well/eat/vitami

Vitamin C - The Nutrition Source | Harvard T.H. Chan School of Public Health
https://www.hsph.harvard.edu/n....utritionsource/vitam

If you feel like you are actually experiencing a real-life medical emergency, immediately stop watching and call 9-11 or contact a medical professional. The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. The satirical nature presented in the video is for entertainment purposes and does not endorse the actions displayed. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace an appointment with your own personal doctor.

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Check out these surprising things you need to know about vitamin C! Check out Dr. Berg’s Vitamin C Complex Here: 🛒 https://bit.ly/3tZrDi0 OR https://amzn.to/3DwYTQG

DATA:
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https://www.sciencedirect.com/....science/article/pii/

0:00 Introduction: Vitamin C explained
0:05 What is ascorbic acid?
1:45 Surprising things about vitamin C
8:10 Check out my video on what vitamin C does!

Today, let’s talk about vitamin C. I want to increase your awareness of the type of vitamin C you might be taking and the type you should be taking.

According to recent editions of the dictionary, ascorbic acid is the same thing as vitamin C. But, is the type of ascorbic acid in most vitamin supplements actually similar to vitamin C found in nature?

In my opinion, no. Ascorbic acid (synthetic vitamin C) is made from glucose and other chemicals. Personally, I would only take ascorbic acid for a short-term detox cleanse, not on a long-term basis.

The best type of vitamin C to get is vitamin C from food or food-based vitamins.

Foods that have the most vitamin C:
• Leafy greens
• Berries
• Lemons
• Organ meats
• Bell peppers
• Sauerkraut

Things you need to know about vitamin C:
1. There is little to no benefit from taking high doses of ascorbic acid.

2. Most vitamin C sold is fake and made from sugar.

3. Vitamin C is not absorbed well if you consume sugar at the same time.

4. A mega-dose of ascorbic acid may cause oxidation, diarrhea, and bloating.

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Dr. Eric Berg DC Bio:
Dr. Berg, age 56, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.

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Disclaimer:
Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients so he can focus on educating people as a full time activity, yet he maintains an active license. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition.

#keto #ketodiet #weightloss #ketolifestyle

Thanks for watching! I hope this helps you better understand vitamin C and what type of vitamin C to take.

➡️BEST FOODS FOR VITAMIN C.
➡️VITAMIN C RICH FOODS.
➡️FOOODS FOR VITAMIN C.

Is Vitamin C a miracle ingredient? How, when, and why to use it in your routine!

0:00 intro
0:44 benefits of vitamin c
3:18 active vs. inactive forms
3:42 l-ascorbic acid
6:09 ester forms
8:20 non ester forms


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Kicking off the year with a bright start! We're getting back to basics to relearn good habits when it comes to Vitamin C so that you can get the biggest bang for your buck in your routine.

1:14 vitamin c marketing
2:21 benefits of vitamin c
6:05 what to look for
9:56 when and how to use it

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In the latest episode of "Talking with Docs," the focus turns to the contentious topic of Vitamin C and its efficacy in preventing illness or halting its progression. The doctors delve into the scientific literature, weighing the evidence for and against Vitamin C's purported benefits. They explore its potential as a preventative measure against sickness, as well as its ability to mitigate symptoms and shorten the duration of illnesses. With a blend of medical expertise and candid discussion, the episode offers viewers a comprehensive understanding of the role Vitamin C plays in immune health and its real-world impact on staying well.

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Medical emergency
Do NOT use the Video for medical emergencies. If you have a medical emergency, call a physician or qualified healthcare provider, or CALL 911 immediately. Under no circumstances should you attempt self-treatment based on anything you have seen or read on the Video.

General information is not medical advice
The general information provided on the Video is for informational purposes only and is not professional medical advice, diagnosis, treatment, or care, nor is it intended to be a substitute therefore. Always seek the advice of your physician or other qualified health provider properly licensed to practice medicine or general healthcare in your jurisdiction concerning any questions you may have regarding any information obtained from this Video and any medical condition you believe may be relevant to you or to someone else. Never disregard professional medical advice or delay in seeking it because of something you have read on this Video. Always consult with your physician or other qualified healthcare provider before embarking on a new treatment, diet, or fitness program. Information obtained on the Video is not exhaustive and does not cover all diseases, ailments, physical conditions, or their treatment


#vitaminc #skincare #vitamin #vitamine #vitamins #collagen #beauty #covid #health #healthylifestyle #vitamind #skincareroutine #jerawat #antiaging #mg #vitaminb #shaklee #glutathione #glowingskin #serum #shakleemalaysia #skin #vitamincserum #vitc #healthy #supplements #wellness #glutax #esp #kulitcantik

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Vitamin D supplementation and incident dementia: Effects of sex, APOE, and baseline cognitive status

https://alz-journals.onlinelib....rary.wiley.com/doi/1

Alberta, Canada

Known association, vitamin D deficiency, incident dementia

https://nutritionj.biomedcentr....al.com/articles/10.1
Role of supplementation is unclear.

Prospectively study

Associations, vitamin D supplementation and incident dementia

N = 12,388 dementia-free people

(from the National Alzheimer's Coordinating Center)

Methods

Baseline exposure to vitamin D was considered D+

No exposure prior to dementia onset was considered D−

MCI and depression were both more frequent in the D− group, compared to D+

People taking vitamin D had less MCI and less depression

Adjusted for age, sex, education, race, cognitive diagnosis, depression, and apolipoprotein E (APOE) ε4.

Potential interactions between exposure and model covariates were explored.

Results

Across all formulations,

vitamin D exposure was associated with significantly longer dementia-free survival,

and lower dementia incidence rate than no exposure

Hazard ratio = 0.60

(95% confidence interval:
0.55–0.65)

Vitamin D exposure was associated with 40% lower dementia incidence versus no exposure.

Over 10 year follow up of

12,388

2,696 participants progressed to dementia

Among them the 2,696

2,017 (74.8%) had no exposure to vitamin D

679 (25.2%) had baseline exposure

Exposure to vitamin D was associated with significantly higher dementia-free survival

5-year survival for D− was 68.4%

5-year survival for D+ was 83.6%

The effect of vitamin D on incidence rate differed significantly,

Vitamin D effects were significantly greater in females versus males

Vitamin D effects were significantly greater in normal cognition versus mild cognitive impairment.

Vitamin D effects were significantly greater in apolipoprotein E ε4 non-carriers versus carriers.

Vitamin D effects were less significantly apolipoprotein E ε4 carriers. (25% one copy, 3% two copies)

Vitamin D has potential for dementia prevention, especially in the high-risk strata.

Vitamin D deficiency, worldwide prevalence of up to 1 billion.

https://www.sciencedirect.com/....science/article/pii/

Mechanism of action

https://www.nature.com/articles/s41430-020-0558-y

Vitamin D is known to participate in the clearance of amyloid beta (Aβ) aggregates,

one of the hallmarks of Alzheimer's disease (AD),

and may provide neuroprotection against Aβ-induced tau hyperphosphorylation

(neurofibrillary tangles)

Cholecalciferol may be more effective than ergocalciferol

In this video the surgeons provide an update on the use of vitamin D. They discuss it's role in bone health, the immune system, the cardiovascular system, and even reducing anxiety and depression.
Please see the complete user agreement at talkingwithdocs.com

Vitamin D is important for several reasons. It helps the body absorb and use calcium and phosphorus, which are essential for building and maintaining strong bones and teeth. Vitamin D also plays a role in regulating the immune system, supporting brain function, and reducing inflammation in the body. In addition, some studies suggest that adequate levels of vitamin D may help protect against certain diseases, such as cancer, diabetes, and multiple sclerosis.

Medical emergency
Do NOT use the Video for medical emergencies. If you have a medical emergency, call a physician or qualified healthcare provider, or CALL 911 immediately. Under no circumstances should you attempt self-treatment based on anything you have seen or read on the Video.

General information is not medical advice
The general information provided on the Video is for informational purposes only and is not professional medical advice, diagnosis, treatment, or care, nor is it intended to be a substitute therefore. Always seek the advice of your physician or other qualified health provider properly licensed to practise medicine or general healthcare in your jurisdiction concerning any questions you may have regarding any information obtained from this Video and any medical condition you believe may be relevant to you or to someone else. Never disregard professional medical advice or delay in seeking it because of something you have read on this Video. Always consult with your physician or other qualified healthcare provider before embarking on a new treatment, diet, or fitness program. Information obtained on the Video is not exhaustive and does not cover all diseases, ailments, physical conditions, or their treatment.

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#vitamind #vitamind3benifits #vitaminddeficiency #vitaminecapsulesforskin #healthylifestyle #health #vitamins #vitamin #sunshine #vitaminb #tanning #vitamine #sun #supplements #omega #sop #nutrition #wellness #fitness #healthy #skincare #tan #eskayviediffenz #healthyliving #calcium #kitaikhtiar #cendawansusuharimau #multivitamin #batuk #zinc #makanantambahan #diffenz

Consultant Physician, medical researcher and author, Dr David Grimes conducted much original research on the essential to life Vitamin D. Buy his inexpensive latest book here. https://yorkbookshop.com/healt....h-and-personal-devel

2 minor corrections - 150nmol/L = 60ng/mL (not 80ng/mL as stated and at 2min 27secs)

57min 11 secs Calcifidiol appears in the BNF here:

https://bnf.nice.org.uk/drugs/....calcifediol-monohydr
and medicinal form here
https://bnf.nice.org.uk/drugs/....calcifediol-monohydrmedicinal-forms/

The sunshine vitamin, good ol' Vitamin D. It's one of the biggest health benefits of sunlight exposure. But how do we go from a sun shiny day to creation of an entire nutrient?

☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️

🔗 L I N K S 🔗
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📽 O T H E R V I D E O S 📽
⚰️Medical History playlist: https://www.youtube.com/playli....st?list=PL2rpvfNeooN
🔬Anatomy Basics playlist: https://www.youtube.com/playli....st?list=PL2rpvfNeooN
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📜 S O U R C E S 📜
From Vitamin D to hormone D: fundamentals of the vitamin D endocrine system essential for good health (2008)
https://academic.oup.com/ajcn/....article/88/2/491S/46
Effects of vitamin D supplementation on symptoms of depression in overweight and obese subjects: randomized double blind trial (2008)
https://onlinelibrary.wiley.co....m/doi/full/10.1111/j
Vitamin D deficiency in adults (2010)
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC29127
Adiposity, cardiometabolic risk, and vitamin D (2010)
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC27979
UV light may contribute to geographic and racial blood pressure differences (1997)
https://www.ahajournals.org/do....i/full/10.1161/01.HY
Vitamin D: the “sunshine” vitamin (2012)
https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC33569
Vitamin D deficiency healthline
https://www.healthline.com/nut....rition/vitamin-d-def

💊A B O U T 💊
Hi, I’m Patrick. I’m a freelance science writer based in the San Francisco Bay Area. I hold a bachelor’s degree in Athletic Training and a master’s in clinical exercise physiology. I used to work in the clinical setting as a certified athletic trainer, physical therapy aide, and a certified strength and conditioning specialist. After working in the clinical setting, I went back to school and became a teacher. The goal of my content is to help normal people, not just pre-med students, learn about the human body. That might mean explaining a topic from an anatomy class or exploring a topic from medical history.

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Dr. Dawn-Elise Snipes discusses 23 Surprising Benefits of Vitamin D and Consequences of Low Vitamin D including mood and immunity improvement. DocSnipes is a Licensed Professional Counselor and Qualified Clinical Supervisor. She received her PhD in Mental Health Counseling from the University of Florida in 2002. In addition to being a practicing clinician, she has provided training to counselors, social workers, nurses and case managers internationally since 2006 through AllCEUs.com 23 Surprising Benefits of #VitaminD #vitamind3 #lowvitamind
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#vitamind #winterblues #depressionrelief
Peer Reviewed Articles referenced in this presentation can be found here https://pubmed.ncbi.nlm.nih.gov/?term=vitamin+d&filter=simsearch2.ffrft&filter=years.2012-2022

And specifically as it relates to psychiatric issues here https://pubmed.ncbi.nlm.nih.gov/?term=vitamin+d+psychiatric&filter=simsearch2.ffrft


Join this channel to get access to perks:
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Chapters:
00:00:00 - 23 Benefis yang Tidak Diketahui dari Vitamin D
00:02:12 - Factors that contribute to Vitamin D Deficiency
00:04:36 - Vegan Sources of Vitamin D
00:06:45 - The Benefits of Vitamin D on Health
00:09:05 - Vitamin D and Mood, Autoimmunity, and Inflammation
00:11:27 - The Role of Vitamin D in Estrogen Receptor Positive Breast Cancer
00:13:52 - Vitamin D and Omega-3 Fatty Acids Administration
00:16:06 - Natural Sources of Vitamin D
00:18:28 - Latitude and Vitamin D Synthesis
00:20:47 - Correlation between Vitamin D Deficiencies and Health Problems
NOTE: ALL VIDEOS are for educational purposes only and are NOT a replacement for medical advice or counseling from a licensed professional.

Video by Dr. Dawn Elise Snipes on integrative behavioral health approaches including counseling techniques and skills for improving mental health and reducing mental illness.

AllCEUs.com provides multimedia counselor education and CEUs for LPCs, LMHCs, LMFTs and LCSWs as well as addiction counselor precertification training and continuing education on many of the videos on this channel.

Definitive Evidence from Meta-Analysis and Trial Sequential Analysis

https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC98642

(Italy)

Various studies, a association between severe vitamin D deficiency and bad COVID-19 outcomes.

Vitamin D plays a crucial role in immune function and inflammation.

Recent data suggest a protective role of vitamin D against bad outcomes

Nutraceutical approach

Promote the immune response and reduce the inflammatory response

Anti-inflammatory, antioxidant, and immunomodulatory properties of vitamin D

Immune optimisation and immune boosting

Vitamin D maintains pulmonary barrier function

Determines the production of antimicrobial peptides

Enhances neutrophil activity

Shifts the adaptive immune response to a more T helper cell-2 type

Anti-inflammatory effects of vitamin D

Reduces the production of pro-inflammatory cytokines,

such as IL-6, IL-8, IL-9, IL-12, TNF alfa, IFN gamma

Increases production of anti-inflammatory cytokines,

such as IL-4, IL-5, IL-10

Patients with a low baseline vitamin D, more benefit

Reduce risk of asthma exacerbations

Prevents acute respiratory infections,

and reducing their complications

COVID-19 and vitamin D (Co-VIVID study): a systematic review and meta-analysis of randomized controlled trials

https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC88621

The rates of RT-CR positivity were significantly decreased in the intervention group as compared to the non-vitamin D groups

(RR = 0.46)

Conclusively, COVID-19 patients supplemented with vitamin D, fewer rates of ICU admission, mortality events, and RT-PCR positivity.

Meta-analysis and trial sequential analysis (TSA)

Better explain the strength of association

Protective role of vitamin D supplementation,

and risk of mortality / admission to intensive care units

We searched four databases on 20 September 2022.

Screened the randomized clinical trials (RCTs)

Assessed the risk of bias

(how to adjust thresholds for significance in randomised clinical trials when the required sample size has not been reached)

The pre-specified outcomes of interest

Mortality and ICU admission

78 bibliographic citations

Five RCTs were suitable for our analysis

Results

Vitamin D administration results in a decreased risk of death, 0.49

Vitamin D administration results in a decreased risk of ICU admission, 0.28

Protective role of vitamin D and ICU admission

The TSA of the protective role of vitamin D and ICU admission showed that, since the pooling of the studies reached a definite sample size, the positive association is conclusive.

The studies

Effects of a 2-Week 5000 IU versus 1000 IU Vitamin D3 Supplementation on Recovery of Symptoms in Patients with Mild to Moderate Covid-19: A Randomized Clinical Trial

https://www.mdpi.com/2072-6643/13/7/2170

(Saudi)

Effect of calcifediol treatment and best available therapy versus best available therapy on intensive care unit admission and mortality among patients hospitalized for COVID-19: A pilot randomized clinical study

https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC74561

(Spain)


Changes in the immune response against SARS-CoV-2 in individuals with severe COVID-19 treated with high dose of vitamin D

https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC90081

(Spain)

Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19

https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC78904

(Brazil)

Calcifediol treatment and COVID-19-related outcomes

https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC83446

(Spain)

Medicines & Healthcare products
Regulatory Agency

https://www.bmj.com/content/377/bmj.o1538

86% industry funded

Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes, (7th Feb 2023)

https://www.acpjournals.org/doi/10.7326/M22-3018?utm_source=cmpnr&utm_campaign=lfa_230207_a&utm_content=3&cmp=1&utm_medium=email

HTTPS://WWW.ACPJOURNALS.ORG/DOI/10.7326/P22-0031?UTM_SOURCE=CMPNR&UTM_CAMPAIGN=LFA_230207_A&UTM_CONTENT=3&CMP=1&UTM_MEDIUM=EMAIL

Vitamin D has many functions in the body,

including a role in insulin secretion and glucose metabolism.

Observational studies,

association between low level of vitamin D in the blood,

and high risk for developing diabetes.

So, does giving vitamin D to people who were at high risk for diabetes reduce the risk?

Authors searched 3 databases,

through 9 December 2022

Compare the use of vitamin D versus placebo for diabetes prevention,

in adults with prediabetes.

Meta analysis and reanalysis of pooled data

Trials were at low risk for bias

Results

Over 3 years of follow-up

Vitamin D group

New-onset diabetes occurred in 22.7%

Placebo group

New-onset diabetes occurred in 25%

Translates to being 15% reduction

Number needed to treat to prevent one case of diabetes

30 adults with prediabetes to prevent 1 person from developing diabetes.

Risk reduction by blood levels

At least 125 nmol/L (≥50 ng/mL) group

50 to 74 nmol/L (20 to 29 ng/mL) group

Cholecalciferol reduced risk for diabetes by 76%

(hazard ratio, 0.24)

3-year absolute risk reduction of 18.1%

Vitamin D increased the likelihood of regression to normal glucose regulation by 30%

Doses used

20,000 units of cholecalciferol (vitamin D3) weekly

4000 units of cholecalciferol daily

0.75 micrograms of eldecalcitol, (synthetic analogue of vitamin D)

Adverse events

Rare, study could not draw any definite conclusions about safety

kidney stones

hypercalcemia

hypercalciuria

Implications

In adults with prediabetes,
vitamin D was effective in lowering the risk for developing diabetes.

By the Numbers: Diabetes in America

https://www.cdc.gov/diabetes/h....ealth-equity/diabete

Total Diabetes

From 2001 to 2020,

diabetes prevalence significantly increased among over 18s

37.3 million people have diabetes

(11.3% of the US population).

28.7 million people have been diagnosed with diabetes.

8.5 million people who have diabetes have not been diagnosed

(do not know they have it)

Total Prediabetes

96 million US adults have prediabetes.

Cost of Diabetes (2017)

$327 billion,

$237 billion direct medical costs

$90 billion in lost productivity

Excess medical costs, $9,601 per person













https://www.diabetes.org.uk/pr....ofessionals/position

UK prevalence

4.8 million (7%)

3.9 million diagnosed

1 million undiagnosed

5.3 million by 2025

People with type 2 diabetes

50% more likely to die prematurely

Two-and-a-half times more likely to. Develop heart failure

Twice more likely to have a heart attack

Obesity, sugars, carbohydrates, processed foods, exercise, vitamin D

Join us on 'Talking with Docs' as we discuss whether you should take vitamin K and vitamin D together. Our experts weigh in on the benefits and considerations. Tune in for valuable insights into optimizing your vitamin intake! 💊 #TalkingWithDocs #VitaminsDebate

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General information is not medical advice
The general information provided on the Video is for informational purposes only and is not professional medical advice, diagnosis, treatment, or care, nor is it intended to be a substitute therefore. Always seek the advice of your physician or other qualified health provider properly licensed to practice medicine or general healthcare in your jurisdiction concerning any questions you may have regarding any information obtained from this Video and any medical condition you believe may be relevant to you or to someone else. Never disregard professional medical advice or delay in seeking it because of something you have read on this Video. Always consult with your physician or other qualified healthcare provider before embarking on a new treatment, diet, or fitness program. Information obtained on the Video is not exhaustive and does not cover all diseases, ailments, physical conditions, or their treatment

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